Compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer
AssigneeMillennium Pharmaceuticals, Inc.
InventorsAllison Berger, Tracy L. Guillemette, Barbara Moore Bryant, Michael P. Morrissey, Robert Schlegel
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Abstract
The invention relates to newly discovered nucleic acid molecules and proteins associated with colon cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human colon cancers are provided.
Claims6
An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of SEQ ID NOs:
- 1-29.
An isolated polypeptide which is encoded by a nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of SEQ ID NOs:
- 1-29.
A method of assessing whether a patient is afflicted with colon cancer, the method comprising comparing:
- a) the level of expression of a marker in a patient sample, wherein the marker is selected from the group consisting of n1-n333;
- and
- b) the normal level of expression of the marker in a control non-colon cancer sample,
- wherein a significant increase in the level of expression of the marker in the patient sample and the normal level is an indication that the patient is afflicted with colon cancer.
Dependencies are inferred from the claim text.