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US 2003/0148271 A1Published application
Novel prostate-associated kallikrein
OwnerJennifer L. Hillman, Surya K. Goliinventors
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OwnerJennifer L. Hillman, Surya K. Goliinventors
Estimating the term…
The present invention provides a human prostate-associated kallikrein (HPAK) and polynucleotides which identify and encode HPAK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPAK and a method for producing HPAK. The invention also provides for antibodies or antagonists specifically binding HPAK, and their use, in the prevention and treatment of diseases associated with expression of HPAK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPAK for the treatment of diseases associated with the expression of HPAK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPAK.
A substantially purified prostate-associated kallikrein protein comprising the amino acid sequence of SEQ ID NO:1 or fragments thereof.
An isolated and purified polynucleotide sequence comprising SEQ ID NO:2 or variants thereof.
Dependencies are inferred from the claim text.