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OwnerOlli Tuominen, Eric W. Stroup +2inventors
InventorsOlli Tuominen, Eric W. Stroup, Chih-Hu Ho, Justin W. Cook
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A coating material and a method for coating a hydrophobic membrane with a copolymer that contains at least one hydrophilic segment and at least one hydrophilic segment, such as a PEO—PPO—PEO triblock copolymer, so that the surface of the membrane becomes hydrophilic. The hydrophilic coating helps repel biological molecules, thereby reducing the risk that these molecules will adsorb or deposit on the membrane surface. When the copolymers are modified with an active group, ligands can be immobilized on the copolymer through the active group so that specific molecules that will bind with the ligands can be targeted for immobilization on the copolymer coating, thereby improving the efficiency of the removal of specific targets.
A coated membrane for use in dialysis, hemodialysis, hemofiltration, hemodiafiltration or other end stage renal disease treatments comprising a hydrophobic membrane wherein at least one copolymer is attached to said hydrophobic membrane, and each copolymer is comprised of at least one hydrophobic segment and at least one hydrophilic segment.
A dialyzer for use in dialysis, hemodialysis, hemofiltration, hemodiafiltration or other end stage renal disease treatments having a hydrophobic membrane with at least one copolymer attached to said hydrophobic membrane, wherein said copolymer is comprised of at least one hydrophobic segment and at least one hydrophilic segment attached to said hydrophobic segment at its first end.
A method for coating a hydrophobic membrane for use in dialysis, hemodialysis, hemofiltration, hemodiafiltration or other end stage renal disease treatments comprising:
A dialysis set for use in dialysis, hemodialysis, hemofiltration, hemodiafiltration or other end stage renal disease treatments comprising a set of tubing, dialysate solution container, at least one pump, and a dialyzer, wherein said dialyzer has a hydrophobic membrane, at least one copolymer is attached to said hydrophobic membrane, and each copolymer is comprised of at least one hydrophobic segment and at least one hydrophilic segment.
A method for reducing the adsorption and deposition of blood constituents on a hydrophobic membrane surface for use in dialysis, hemodialysis, hemofiltration, hemodiafiltration or other end stage renal disease treatments comprising:
A method for performing dialysis, hemodialysis, hemoperfusion, hemodiafiltration or other end stage renal disease treatments using a dialyzer that contains a hydrophobic membrane, wherein at least one copolymer is attached to said hydrophobic membrane and each copolymer is comprised of at least one hydrophobic segment and at least one hydrophilic segment.
A method for performing dialysis, hemodialysis, hemoperfusion, hemodiafiltration or other end stage renal disease treatments comprising:
Dependencies are inferred from the claim text.