Extraction of flavonoids
AssigneeBiorex Health Limited
InventorsRobert Gerard Wallace, Willfrits Gerald Burong
Life of this patent
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Abstract
A method of producing an enriched flavonoid aglycone extract from starting material containing a suitable flavonoid glycoside and/or conjugate thereof comprising the steps of: (i) enzymatically converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone; (ii) adjusting the pH to render the flavonoid aglycone soluble and removing the insoluble fraction; and (iii) adjusting the pH to render the soluble flavonoid aglycone relatively insoluble and forming an extract containing the same.
Claims39
A method of producing an enriched flavonoid aglycone extract from starting material containing a suitable flavonoid glycoside and/or conjugate thereof comprising the steps of:
- (i). enzymatically converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone;
- (ii). adjusting the pH to render the flavonoid aglycone soluble and removing the insoluble fraction;
- and
- (iii). adjusting the pH to render the soluble flavonoid aglycone relatively insoluble and forming an extract containing the same.
A method according to claim I wherein the flavonoid aglycone is rendered soluble by adjusting the pH to approximately 11-12.
A method of producing an enriched flavonoid aglycone extract from a plant or plant material containing a suitable flavonoid glycoside and/or conjugate thereof comprising the steps of:
- (i). enzymatically converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone;
- (ii). adjusting the pH to render the flavonoid aglycone soluble and removing the insoluble fraction;
- and
- (iii). adjusting the pH to render the soluble flavonoid aglycone relatively insoluble and forming an extract containing the same.
A method of producing an enriched flavonoid aglycone extract from plant material containing a flavonoid glycoside and/or conjugate thereof comprising the steps of:
- (i). disrupting the cellular structure of the plant material to contact the flavonoid glycoside or conjugate thereof contained therein with at least one enzyme contained therein adapted to convert the flavonoid glycoside or conjugate thereof to a flavonoid aglycone and thus converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone;
- (ii). adjusting the pH to render the flavonoid aglycone soluble and separating off the insoluble fraction;
- and
- (iii). adjusting the pH to render the flavonoid aglycone relatively insoluble and isolating the flavonoid aglycone.
An enriched flavonoid aglycone extract produced by a method wherein starting material containing a suitable flavonoid glycoside and/or conjugate thereof is treated as follows:
- (i). enzymatically converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone;
- (ii). adjusting the pH to render the flavonoid aglycone soluble and removing the insoluble fraction;
- and
- (iii). adjusting the pH to render the soluble flavonoid aglycone relatively insoluble and forming the extract.
An enriched flavonoid aglycone extract produced by a method wherein plant material containing a suitable flavonoid glycoside and/or conjugate thereof is treated as follows:
- (i). enzymatically converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone;
- (ii). adjusting the pH to render the flavonoid aglycone soluble and removing the insoluble fraction;
- and
- (iii). adjusting the pH to render the soluble flavonoid aglycone relatively insoluble and forming the extract.
An enriched flavonoid aglycone extract produced by a method wherein plant material containing a suitable flavonoid glycoside and/or conjugate thereof is treated as follows:
- (i). disrupting the cellular structure of the plant material to contact the flavonoid glycoside or conjugate thereof contained therein with at least one enzyme contained therein adapted to convert the flavonoid glycoside or conjugate thereof to a flavonoid aglycone and thus converting the flavonoid glycoside or conjugate thereof into the flavonoid aglycone;
- (ii). adjusting the pH to render the flavonoid aglycone soluble and separating off the insoluble fraction;
- and
- (iii). adjusting the pH to render the flavonoid aglycone relatively insoluble and forming the extract.
Dependencies are inferred from the claim text.