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US 2003/0147953 A1Published application
Delayed release anti-fungal product, use and formulation thereof
AssigneeAdvancis Pharmaceutical Corp.
InventorsEdward M. Rudnic, James D. Isbister, Donald J. Treacy JR., Sandra E. Wassink
Life of this patent
Estimating the term…
Abstract
An anti-fungal product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the anti-fungal product being reached in less than about twelve hours after initial release of anti-fungal from the product.
Claims27
An anti-fungal product comprising:
- a first anti-fungal dosage form, a second anti-fungal dosage form, and a third anti-fungal dosage form, each of said first, second and third anti-fungal dosage forms comprising an anti-fungal and a pharmaceutically acceptable carrier, said three dosage forms having different release profiles, said anti-fungal product reaching a Cmax in less than about twelve hours after initial release of anti-fungal and each being a delayed release dosage form.
An anti-fungal product comprising:
- a first anti-fungal dosage form, a second anti-fungal dosage form, and a third anti-fungal dosage form, each of said first, second and third anti-fungal dosage forms comprising an anti-fungal and a pharmaceutically acceptable carrier, said three dosage forms having different release profiles, said anti-fungal product reaching a Cmax in less than about twelve hours after initial release of anti-fungal from the product, said first, second and third dosage forms, each being a delayed release dosage form, wherein the anti-fungal released from the first dosage form reaches a Cmax in serum in from 0.5 to 2 hours after initial release of anti-fungal from the product, wherein the anti-fungal released from the second dosage form reaches a Cmax in serum in no more than about 4 hours after initial release of anti-fungal from the product and after Cmax is reached for anti-fungal from the first dosage form and the anti-fungal released from the third dosage form reaches a Cmax in serum after the Cmax is reached for the anti-fungal released from the second dosage form.
Dependencies are inferred from the claim text.