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AssigneeYamanouchi Pharmaceutical Co., Ltd.
InventorsTatsuki Shinoda, Atsushi Maeda, Naoki Itou, Takao Mizumoto, Shigeru Yamazaki, Yuuki Takaishi
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The present invention relates to a composition comprising sustained-release fine particles, characterized in that it contains sustained-release fine particles that can be used in quick-disintegrating tablets in the buccal cavity, one or more fillers selected from the group consisting of sugars or sugar alcohols, and one or more binders for quick-disintegrating tablets in the buccal cavity selected from the group consisting of sugars of high moldability and water-soluble polymer substances, and in that the sustained-release fine particles are granulated with filler and binder for quick-disintegrating tablets in the buccal cavity, and a manufacturing method thereof.
A composition comprising sustained-release fine particles for quick-disintegrating tablets in the buccal cavity, characterized in that it comprises the product granulation of sustained-release fine particles containing a drug and one or two or more fillers selected from the group consisting of sugars or sugar alcohols with a binder for quick-disintegrating tablets in the buccal cavity, and in that the ratio of ungranulated sustained-release fine particles in the entire composition is 0 to 15%.
A method of manufacturing a composition comprising sustained-release fine particles for quick-disintegrating tablets in the buccal cavity, characterized in that it comprises the product of granulation of sustained-release fine particles containing a drug and one or two or more fillers selected from the group consisting of sugars or sugar alcohols with a binder for quick-disintegrating tablets in the buccal cavity, and in that the ratio of ungranulated sustained-release fine particles in the entire composition is 0 to 15%.
Dependencies are inferred from the claim text.