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US 2003/0147921 A1Published application
Method of targeting pharmaceuticals to motor neurons
AssigneeWisconsin Alumni Research Foundation
InventorsMichael C. Goodnough, Eric A. Johnson, William H. Tepp, Carl J. Malizio
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Abstract
A method of targeting therapeutic molecules to motor neurons is disclosed. In one embodiment, this method comprises the steps of (a) synthesizing a prodrug comprising a therapeutic molecule covalently bound to a polymeric delivery vehicle, and (b) conjugating the prodrug to a botulinum neurotoxin heavy chain.
Claims12
A method of targeting therapeutic molecules to motor neurons, comprising the steps of:
- (a) synthesizing a prodrug comprising at least one therapeutic molecule covalently bound to a polymeric delivery vehicle, and
- (b) conjugating the prodrug to a botulinum neurotoxin heavy chain.
Dependencies are inferred from the claim text.