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US 2003/0147888 A1Published application
Polyvalent immunogen
AssigneesDuke University, The Regents of the University of Calforinia
InventorsBarton F. Haynes, Bette T. Korber, Robert M. De Lorimier
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Abstract
The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against IV and to a polyvalent immunogen suitable for use in such a method.
Claims29
A composition comprising a multiplicity of immunogenic peptides comprising a first and a second component,
- said first component comprising a T-helper epitope,
- said second component comprising residues of the V3 domain of gp120 and including a B cell neutralizing antibody epitope.
A composition comprising at least one peptide from Table 6 or Table 7 and a carrier.
A nucleic acid encoding a peptide in Table 6 or Table 7.
Dependencies are inferred from the claim text.