Novel antibody compositions for preparing enriched dendritic cell preparations
AssigneeStemCell Technologies Inc.
InventorsTerry Thomas, Peter Lansdorp
Life of this patent
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Abstract
The present invention relates to antibody composition that are useful in preparing enriched cell preparations such as human hematopoietic progenitor cells and stem cells and non-hematopoietic tumor cells. The invention also relates to kits for carrying out the processes and to the cell preparations prepared by the processes.
Claims14
A process for enriching and recovering dendritic cells from a sample comprising reacting the sample with an antibody composition containing antibodies capable of binding to the antigens glycophorin A, CD3, CD14, CD16, CD19, CD34, CD56 and CD66b under conditions so that conjugates are formed between the antibodies and the cells in the sample having the antigens glycophorin A, CD3, CD14, CD16, CD19, CD34, CD56 and CD66b on their surfaces;
- removing the conjugates;
- and recovering a cell preparation which is enriched in dendritic cells.
An antibody composition for enriching for dendritic cells comprising antibodies specific for glycophorin A, CD3, CD14, CD16, CD19, CD34, CD56 and CD66b.
Dependencies are inferred from the claim text.