Methods for amyloid removal using anti-amyloid antibodies
OwnerAlan Solomon, Rudi Hrncic +1inventors
InventorsALAN SOLOMON, RUDI HRNCIC, JONATHAN STUART WALL
Life of this patent
Estimating the term…
Abstract
Methods and related immunoglobulin peptides and fragments thereof are disclosed that enhance the cell-mediated immune response of a patient to deposits of amyloid fibrils. These methods exploit the opsonizing effect of antibodies directed toward amyloid material or its component parts.
Claims22
A method of treating a patient having an amyloid deposition disease comprising the step of administering to the patient
- a) a therapeutically effective dose of at least one immunoglobulin polypeptide or a fragments thereof, wherein the immunoglobulin polypeptide or fragment thereof binds to an amyloid fibril;
- and
- b) a pharmaceutically acceptable carrier.
An immunoglobulin polypeptide or fragment thereof that binds to an amyloid fibril and is effective to enhance the cellular immune response of a patient to remove disease-associated amyloid fibril deposits.
Dependencies are inferred from the claim text.