Immunosuppressant
OwnerMasahiro Nagamutainventor
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Abstract
The present invention relates to an immunosuppressant comprising antigen-treated B lymphocytes obtained by contact-treating B lymphocytes with an antigen, a liposome encapsulating or attaching to itself an antigen, or a conjugate of an antigen and a substance which binds to B lymphocytes, or a mixture of at least two of these substances. The present invention also relates to such liposomes and conjugates. The present invention also relates to a method for creating an immunosuppressed animal comprising transferring the immunosuppressant to an animal, and to an immunosuppressed animal created by such methods. The present invention further relates to a method for treating or preventing diseases comprising administering the immunosuppressant to a human.
Claims26
An immunosuppressant comprising antigen-treated B lymphocytes obtained by contact-treating B lymphocytes with an antigen.
An immunosuppressant comprising antigen-treated B lymphocytes obtained by contact-treating B lymphocytes with an antigen, a liposome encapsulating or attaching to itself an antigen, or a conjugate of an antigen and a substance which binds to B lymphocytes, or a mixture of at least two of these materials.
An antigen-containing liposome which is encapsulating or attaching to itself the antigen.
A conjugate of an antigen and a substance which binds to B lymphocytes.
A conjugate of an antigen and a substance which binds to B lymphocytes, obtained by expressing a gene comprising a gene encoding the antigen and a gene encoding the substance which binds to B lymphocytes.
An antigen which is able to induce an immunosuppressive action in B lymphocytes when contact-treated with the B lymphocytes.
Dependencies are inferred from the claim text.