Antisense modulation of TFAP2C expression
AssigneeIsis Pharmaceuticals, Inc.
InventorsLex M. Cowsert, Susan M. Freier
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of TFAP2C. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding TFAP2C. Methods of using these compounds for modulation of TFAP2C expression and for treatment of diseases associated with expression of TFAP2C are provided.
Claims20
A compound 8 to 50 nucleobases in length targeted to a nucleic acid molecule encoding TFAP2C, wherein said compound specifically hybridizes with said nucleic acid molecule encoding TFAP2C and inhibits the expression of TFAP2C.
A compound 8 to 50 nucleobases in length which specifically hybridizes with at least an 8-nucleobase portion of an active site on a nucleic acid molecule encoding TFAP2C.
Dependencies are inferred from the claim text.