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AssigneeWyeth
InventorsNicholas W. Warne, Camille L. Bedrosian, James C. Keith JR., Ullrich S. Schwerschlag, Paul F. Schendel
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Provided by the present invention are topical formulations of Interleukin-11 and methods for treating a variety of disorders, including inflammatory bowel diseases (e.g., Crohn's disease, ulcerative colitis, indeterminate colitis, and infectious colitis), mucositis (e.g., oral mucositis, gastrointestinal mucositis, nasal mucositis, and proctitis), necrotizing enterocolitis, inflammatory skin disorders (e.g., psoriasis, atopic dermatitis, and contact hypersensitivity), aphthous ulcers, pharyngitis, esophagitis, peptic ulcers, gingivitis, periodontitis, and ocular diseases (e.g., conjunctivitis, retinitis, and uveitis).
A method of treating Inflammatory Bowel Disease comprising administering to a patient a topical formulation of a pharmaceutical composition composed of a pharmaceutically effective amount of IL-11 and a carrier for delivery of IL-11 to the gastrointestinal tract.
A method of treating Inflammatory Bowel Disease comprising administering to a patient a topical formulation of a pharmaceutical composition composed of multi-particulate, enteric-coated particles containing a pharmaceutically effective amount of IL-11.
A composition for treating Inflammatory Bowel Disease comprising a topical formulation composed of a pharmaceutically effective amount of IL-11 and a suitable solid carrier.
A composition for treating Inflammatory Bowel Disease comprising a topical formulation composed of multi-particulate, enteric-coated particles containing a pharmaceutically effective amount of IL-11.
Dependencies are inferred from the claim text.