Device and methods for initiating chemical reactions and for the targeted delivery of drugs or other agents
OwnerFriedrich Ueberleinventor
Life of this patent
Estimating the term…
Abstract
The present invention is directed to methods and apparatus for the targeted initiation or deactivation of chemical reactions by an acoustic energy source in a host. Methods and apparatus for the targeted delivery of drugs, diagnostic agents and other compounds using an acoustic energy source are also provided.
Claims57
A method for initiating or deactivating chemical reactions inside a host comprising applying to the host acoustic waves at a peak tensile pressure of −5 MPa to −15 MPa to induce cavitation and produce cavitation bubbles that emit ultra short light pulses upon collapse within the infrared, visible and ultraviolet range, wherein the chemical reactions are sensitive to ultra short light pulses within the infrared, visible or ultraviolet range.
A method for the delivery of a drug or biologic agent in a host comprising applying to the host acoustic waves at a peak tensile pressure of −5 MPa to −15 MPa to induce cavitation and produce cavitation bubbles that emit ultra short light pulses upon collapse within the infrared, visible and ultraviolet range, wherein the chemical reactions are sensitive to ultra short light pulses within the infrared, visible or ultraviolet range and wherein the cavitation transient permeabilization of a cell membrane.
An apparatus for initiating or deactivating chemical reactions at a target inside a host comprising an acoustic wave generator capable of generating waves of a sufficient amplitude at a peak tensile pressure of −5 MPa to −15 MPa to induce cavitation, wherein the chemical reactions are sensitive to ultra short light pulses within the infrared, visible or ultraviolet range, and wherein cavitation bubbles are produced that emit ultra short light pulses upon collapse within the infrared, visible and ultraviolet range.
An implantable drug delivery device comprising
- i) a miniaturized electronic circuit chip
- ii) a sensor,
- iii) a drug or agent storage means and
- iv) an acoustic wave generator capable of generating waves at a peak tensile pressure of −5 MPa to −15 MPA to induce cavitation inside a channel, wherein the channel guides a fluid containing the drug or agent
An implantable bio-sensing device comprising
- i) a miniaturized electronic circuit chip
- ii) a sensor
- iii) an acoustic wave generator capable of generating waves at a peak tensile pressure of −5 MPa to −15 MPa to induce cavitation inside a channel, wherein the channel guides a fluid containing a substance or cells to be analyzed.
Dependencies are inferred from the claim text.