Detection of Alzheimer's amyloid by magnetic resonance imaging
AssigneeNew York University
InventorsThomas Wisniewski, Daniel Turnbull, Einar M. Sigurdsson, Youssef Zaim Wadghiri
Life of this patent
Estimating the term…
Abstract
Alzheimer's disease can be diagnosed in vivo using magnetic resonance imaging. A labeled Aβ peptide or its derivative is injected into the patient to be diagnosed, after which the patient is subjected to magnetic resonance imaging. Both pre-amyloid and amyloid plaques can be detected using this method.
Claims36
A method for diagnosing Alzheimer's disease in vivo comprising injecting a labeled Aβ peptide, functional derivative, fragment, variant, analog, or chemical derivative thereof, into a patient to be diagnosed and imaging preamyloid deposits and plaques using magnetic resonance imaging.
The method according to clam 9 wherein the carrier molecule includes a cholesteryl group.
A method for monitoring amyloid clearing comprising injecting a labeled Aβ peptide, functional derivative, fragment, variant, analog, or chemical derivative thereof, into a patient to be monitored and imaging preamyloid deposits and plaques using magnetic resonance imaging.
The method according to clam 25 wherein the carrier molecule includes a cholesteryl group.
Dependencies are inferred from the claim text.