Diffusion cell with quick release clamp
AssigneeHanson Research Corporation
InventorsRoyal A. Hanson, Bruce E. Renslow, Steven W. Shaw, Jerome S. Elkins
Life of this patent
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Abstract
A diffusion cell to facilitate the automatic or manual removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percantaneous absorption through a membrane of a substance from a donor chamber into a receptor chamber of the diffusion cell. There is utilized a capillary port through which the test aliquot is to be removed. A refilling tube connects also with the receptor chamber to add receptor liquid into the receptor chamber as the test aliquot is being removed. A quick release clamping apparatus secures the donor housing which contains the donor chamber tightly to the main housing of the diffusion cell.
Claims13
A diffusion cell comprising:
- a main housing having a receptor chamber, said receptor chamber having an open top and a closed bottom, said receptor chamber adapted to contain a receptor liquid in sufficient quantity to connect with said open top, a receptor liquid refilling port connecting with said receptor chamber directly adjacent said closed bottom, a sampling port connecting with said receptor chamber intermediate said open top and closed bottom but nearer said open top;
- a thin membrane mounted on said housing extending across said open top effectively closing such;
- a donor housing having a donor chamber connecting with said membrane, a media to be supplied to said donor chamber and in contact with said membrane;
- and
- a quick release clamping apparatus engaging with said donor housing functioning to tightly press said donor housing onto said membrane and said main housing.
A diffusion cell comprising:
- a main housing having a receptor chamber, said receptor chamber having an open top and a closed bottom, said receptor chamber adapted to contain a receptor liquid in sufficient quantity to connect with said open top, a receptor liquid refilling port connecting with said receptor chamber directly adjacent said closed bottom, a sampling port connecting with said receptor chamber intermediate said open top and closed bottom but nearer said open top;
- a thin membrane mounted on said housing extending across said open top effectively closing such;
- a donor housing having a donor chamber connecting with said membrane, a media to be supplied to said donor chamber and in contact with said membrane;
- and
- said sampling port including a capillary tube, the function of said capillary tube to minimize the residual volume of a sample that has been extracted through said sampling port.
A diffusion cell comprising:
- a main housing having a receptor chamber, said receptor chamber having an open top and a closed bottom, said receptor chamber adapted to contain a receptor liquid in sufficient quantity to connect with said open top, a receptor liquid refilling port connecting with said receptor chamber directly adjacent said closed bottom, a sampling port connecting with said receptor chamber intermediate said open top and closed bottom but nearer said open top;
- a thin membrane mounted on said housing extending across said open top effectively closing such;
- a donor housing having a donor chamber connecting with said membrane, a media to be supplied to said donor chamber and in contact with said membrane;
- and
- said donor housing including a disc which includes a center opening, said donor housing also including a cap which is mounted onto said disc, said donor chamber comprising said center opening.
Dependencies are inferred from the claim text.