Preparation of pharmaceutical salts

A process for preparing a mixture of rotamer 1 and rotamer 2 of the maleate salt of the compound of Formula I wherein the molar percent of said rotamer 2 to the molar percent of said rotamer 1 in said mixture is in at

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• least about a 55:45 ratio, said process comprising:
• (a) preparing a first intimate mixture of said compound of Formula I in a solvent;
• (b) maintaining said first intimate mixture at about ambient temperature to about 90° C.;
• (c) preparing a second intimate mixture of maleic acid in the same solvent stated in step (a);
• (d) combining said first intimate mixture and said second intimate mixture to prepare a combined intimate mixture and maintaining the combined intimate mixture at about ambient temperature to about 90° C. for about 1-24 hours to induce formation of the maleate salt;
• and
• (e) isolating the salt.

An acid salt of a basic compound, wherein said basic compound has the formula:

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• and wherein said acid salt is selected from the group consisting of acetate, benzenesulfonate, benzoate, bicarbonate, bromide, calcium edetate, camphorsulfonate, carbonate, chloride/dihydrochloride, citrate, N,N-di(dehydroabietyl)ethylenediamine, edetate, 1,2-ethanedisulfonate, ethanesulfonate, fumarate, glucoheptonate, gluconate, glutamate, p-glycollamidophenylarsonate, hexylresorcinate, hyclate, hydrobromide, hydrochloride, 2-hydroxyethanesulfonate, hydroxynaphthoate, iodide, lactate, lactobionate, lauryl sulfonate, malate, maleate, mandelate, methanesulfonate, methylbromide, methylnitrate, methylsulfate, mucate, nafate, napsylate, nitrate, pamoate, pantothenate, phosphate/diphosphate, polygalacturonate, salicyclate, sodium succinate, stearate, subacetate, succinate, sulfate, tosylate, tannate, tartarate/bitartarate, 8-chlorotheophyllinate, triethiodide, adipate, alginate, aminosalicyclate, anhydromethylenecitrate, arecoline, asparate, bisulfate, butylbromide, camphorate, digluconate, dihydrobromide, disuccinate, glycerophosphate, hemisulfate, hydrofluoride, hydroiodide, methylenebis(salicyclate), naphthalenedisulfonate, oxalate, pectinate, persulfate, phenylethylbarbiturate, picrate, propionate, thiocyanate, undecanoate, acetylaminoacetate, N-acetyl-L-asparaginate, N-acetylcystinate, adamantoate, adipoate, N-alkylsulfamates, anthraquinone-1 ,5-disulfonate, arabolactansulfate, argininate, aspartate, betaine, carnitine, 4-chloro-m-toluenesulfonate, decanoate, diacetyl sulfate, dibenzylethylenediamine, dimethylamine, diguaiacylphosphate, dioctylsulfosuccinate, pamoate, fructose-1,6-diphosphate, glucose phosphate, L-glutaminate, hydroxynaphthoate, lauryl sulfate, lysine, 2-naphthenesulfonate, octanonate, tannate and theobromine acetate.