Matrix solid-phase organic synthesis
OwnerMorten Meldal, Leslie P. Mirandainventors
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OwnerMorten Meldal, Leslie P. Mirandainventors
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The present invention relates to a polymer matrix comprising a backbone of linked macromonomers, wherein said macromonomers are selected from the group consisting of triethylene glycols, tetraethylene glycols, and pentaethylene glycols, including any derivative and/or combination thereof. The polymer matrix of the present invention has a high-loading capacity while still being able to swell in small volumes of organic and aqueous solvents; it forms beads effectively so as to provide a resin of homogeneous size and shape; and it is more stable both chemically and physically than state of the art resins. One preferred type of SPOCC resin according to the present invention comprises short chained ethylene glycol macromonomers, including tetraethylene glycol (TEG194), or derivatives thereof.
Polymer matrix comprising a backbone of cross-linked macromonomers, wherein said macromonomers are selected from the group consisting of triethylene glycols, tetraethylene glycols, and pentaethylene glycols, including any combination thereof.
Polymer matrix acceding to any of the previous claims, wherein said matrix has a spherical form.
Dependencies are inferred from the claim text.