Antimalarial N,N'-subistituted biguanides derived from hydroxylamines
AssigneeJacobus Pharmaceutical Company, Inc.
InventorsDavid P. Jacobus, Norman P. Jensen
Life of this patent
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Abstract
Compounds of the formulae 1 a method of protecting subjects from infections caused by an organism of the group: Plasmodium sp. Mycobacterium sp., P. falciparum, M. avium complex, M. tuberculosis, M. Kanasii and Pneumocystis carinii by administering to the subjects liable to infections, a prophylactically effective amount of a compound of the foregoing formulae; and a method of reducing the level of infection in subjects caused by the above-listed organism by administering to the subjects an infection reductively effective amount of a compound of the foregoing formulae.
Claims22
A compound of the formula
- 9
- or a pharmaceutically acceptable salt thereof.
A compound of the formula:
- 10
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.