Cholesterol-lowering agents as treatment for psychological and cognitive disorders
OwnerPerry F. Renshaw, Bruce M. Coheninventors
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Abstract
Provided are methods for treating a membrane fluidity-related cognitive or psychological disorder in a human patient. The methods include the steps of: (a) performing a diagnostic test on the patient to determine that the patient has a cognitive or psychological disorder, and (b) administering to the patient a cholesterol-lowering agent in an amount sufficient to lower the serum cholesterol of the patient enough to increase brain membrane fluidity adequately to treat the cognitive or psychological disorder.
Claims33
A method of treating a membrane fluidity-related cognitive disorder in a human patient, said method comprising the steps of:
- a) performing a diagnostic test on said patient to determine that said patient has a cognitive disorder, and
- b) administering a cholesterol-lowering agent to said patient in an amount sufficient to lower the serum cholesterol of said patient sufficiently to increase brain membrane fluidity sufficiently to treat said cognitive disorder.
A method of treating a membrane fluidity-related affective disorder in a human patient, said method comprising the steps of:
- a) performing a diagnostic test to determine that the patient has a membrane fluidity-related affective disorder, and
- b) administering a cholesterol-lowering agent to said patient in an amount sufficient to lower the serum cholesterol of said patient sufficiently to increase brain membrane fluidity sufficiently to treat said affective disorder.
A method of treating a membrane fluidity-related substance abuse disorder in a human patient, said method comprising the steps of:
- a) performing a diagnostic test to determine that the patient has a membrane fluidity-related substance abuse disorder, and
- b) administering a cholesterol-lowering agent to said patient in an amount sufficient to lower the serum cholesterol of said patient sufficiently to increase brain membrane fluidity sufficiently to treat said substance abuse disorder.
Dependencies are inferred from the claim text.