Remedies

A therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient at least one compound selected from the group consisting of a compound represented by the following general formula (1):

• 32
• wherein each of R1, R2, R3, R4 and R5, which may be identical or different, is hydrogen atom, hydroxyl group, an alkoxy group or an acyloxy group;
• X is a group represented by the following general formula (2):
• 33
• wherein Z is hydrogen atom or an aliphatic group, an aromatic group or an aromatic-aliphatic group, wherein a characteristic group may be introduced into said aliphatic group, said aromatic group or said aromatic-aliphatic group;
• Y is hydrogen atom or hydroxyl group;
• and each of m and n is 0 or 1;
• a group represented by the following general formula (3):
• 34
• wherein Z′ is hydrogen atom or an aliphatic group, an aromatic group or an aromatic-aliphatic group, wherein a characteristic group may be introduced into said aliphatic group, said aromatic group or said aromatic-aliphatic group;
• Y′ is hydrogen atom or hydroxyl group;
• and each of m and n is 0 or 1;
• or a group represented by the following general formula (4):
• 35
• wherein each of R6 and R7, which may be identical or different, is hydrogen atom, a sugar residue, or an aliphatic group, an aromatic group or an aromatic-aliphatic group, wherein a characteristic group may be introduced into said aliphatic group, said aromatic group or said aromatic-aliphatic group, excluding a case where R1, R4 and R5 are all hydrogen atoms, R2 and R3 are all hydroxyl groups, and X is represented by said general formula (2) in said general formula (1), wherein n is 1, m is 0, and Z and Y are hydrogen atom in said general formula (2),
• and pharmacologically acceptable salts thereof.