Antisense modulation of B-cell associated protein expression
AssigneeIsis Pharmaceuticals, Inc.
InventorsC. Frank Bennett, Kenneth Dobie
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of B-cell associated protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding B-cell associated protein. Methods of using these compounds for modulation of B-cell associated protein expression and for treatment of diseases associated with expression of B-cell associated protein are provided.
Claims20
A compound 8 to 50 nucleobases in length targeted to a nucleic acid molecule encoding B-cell associated protein, wherein said compound specifically hybridizes with said nucleic acid molecule encoding B-cell associated protein and inhibits the expression of B-cell associated protein.
A compound 8 to 50 nucleobases in length which specifically hybridizes with at least an 8-nucleobase portion of an active site on a nucleic acid molecule encoding B-cell associated protein.
Dependencies are inferred from the claim text.