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US 2003/0144177 A1Published application
Methods of identifying therapeutic compounds in a genetically defined setting
AssigneeBernhard O. Palsson
InventorBernhard O. Palsson
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Abstract
The invention provides a method of identifying therapeutic compounds in a genetically defined setting. The method consists of contacting a cell indicative of a pathological condition from a diseased individual and a cell from a genetically related normal individual with a plurality of candidate therapeutic compounds under suitable assay conditions, and identifying a compound that preferentially alters a predetermined property of the cell from the diseased individual.
Claims10
A method of identifying a therapeutic compound potentially effective against a predetermined pathological condition, comprising:
- (a) contacting a cell indicative of said pathological condition from a diseased individual with a plurality of candidate therapeutic compounds under suitable assay conditions;
- (b) contacting a cell indicative of said pathological condition from a normal individual, genetically related to said diseased individual, with said plurality under said assay conditions;
- and
- (c) identifying a compound from said plurality that preferentially alters a predetermined property of said cell from said diseased individual, said compound being characterized as a therapeutic compound potentially effective against said pathological condition.
1 more element
Dependencies are inferred from the claim text.