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US 2003/0144139 A1Published application
Novel phosphine compound, transition metal complex containing the same phosphine compound as ligand and asymmetric synthesis catalyst containing the complex
AssigneeTakasago International Corporation
InventorsHideo Shimizu, Takao Saito
Life of this patent
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Abstract
A phosphine compound of formula (1) 1 and a phosphine compound of formula (2) 2 a transition metal complex having the phosphine compound as a ligand and a catalyst for asymmetric hydrogenation including the transition metal complex.
Claims14
A phosphine compound of the formula (1):
- 9
- where R1 is a linear or branched alkyl group having 1 to 5 carbon atoms, R2 and R3 represent independently a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, R4, R5, R6 and R7 represent independently a hydrogen atom, a halogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, or a dialkylamino group where the alkyl has 1 to 5 carbon atoms, X represents a functional group that forms a stable bond with phosphorous atom, with the proviso that R4 and R5 or R5 and R6 or R6 and R7 taken together with the carbon atoms to which they are attached optionally form a ring or fused ring.
A phosphine compound of the formula (2):
- 10
- where R1 is a linear or branched alkyl group having 1 to 5 carbon atoms;
- R2 and R3 represent independently a hydrogen atom or an alkyl group having 1 to 5 carbon atoms;
- R4, R5, R6 and R7 represent independently a hydrogen atom, a halogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, or a dialkylamino group, where the alkyl has 1 to 5 carbon atoms, with the proviso that R4 and R5 or R5 and R6 or R6 and R7 taken together with the carbon atoms to which they are attached optionally form a ring or fused ring;
- R11 is a linear or branched alkyl group having 1 to 5 carbon atoms, R21 and R31 represent independently a hydrogen atom or an alkyl group having 1 to 5 carbon atoms;
- R41, R51, R61 and R71 represent independently a hydrogen atom, a halogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, a dialkylamino group, where the alkyl has 1 to 5 carbon atoms, Y represents a functional group that forms a stable bond with phosphorous atom;
- with the proviso that R41 and R51 or R51 and R61 or R61 and R71 taken together with the carbon atoms to which they are attached optionally form a ring or fused ring.
4 more elements
Dependencies are inferred from the claim text.