Back to results
US 2003/0143708 A1Published application
Method and reagent for the treatment of alzheimer's disease
OwnerLa Wrence Blatt, James A. McSwiggeninventors
Life of this patent
Estimating the term…
Abstract
Nucleic acid molecules, including antisense and enzymatic nucleic acid molecules, such as hammerhead ribozymes, DNAzymes, and antisense, which modulate the expression of molecular targets impacting the development and progression of Alzheimer's disease, in particular, the expression of BACE and ps-2 gene.
Claims55
An enzymatic nucleic acid molecule which down regulates expression of a beta site APP-cleaving enzyme (BACE) gene.
A nucleic acid molecule which down regulates expression of a presenilin (ps-2) gene.
An antisense nucleic acid molecule comprising sequence complementary to any of the sequences defined as sequence ID Nos. 1-1775.
Dependencies are inferred from the claim text.