Human skeletal muscle-specific ubiquitin-conjugating enzyme
AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorsTsutomu Fujiwara, Takeshi Watanabe, Masato Horie
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Abstract
The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
Claims24
A GDP dissociation stimulating protein gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1.
A GDP dissociation stimulating protein gene comprises the nucleotide sequence shown under SEQ ID NO:2.
A brain-specific nucleosome assembly protein gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:19.
A brain-specific nucleosome assembly protein gene comprises a nucleotide sequence shown under SEQ ID NO:20.
A human skeletal muscle-specific ubiquitin-conjugating enzyme gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:22.
A human skeletal muscle-specific ubiquitin-conjugating enzyme gene comprises the nucleotide sequence shown under SEQ ID NO:23.
A TMP-2 gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:25.
A TMP-2 gene comprises the nucleotide sequence shown under SEQ ID NO:26.
A human NPIK gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:28.
A human NPIK gene comprises the nucleotide sequence shown under SEQ ID NO:29.
A human NPIK gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:31.
A human NPIK gene comprises the nucleotide sequence shown under SEQ ID NO:32.
A nel-related protein type 1 gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:34.
A nel-related protein type 1 gene comprises the nucleotide sequence shown under SEQ ID NO:35.
A nel-related protein type 2 gene comprises a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:37.
A nel-related protein type 2 gene comprises the nucleotide sequence shown under SEQ ID NO:38.
Dependencies are inferred from the claim text.