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AssigneeFuji Photo Film Co., Ltd.
InventorNobuhiko Ogura
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A method for conducting a receptor-ligand association reaction includes the steps of dipping a biochemical analysis unit including a substrate formed with a plurality of absorptive regions which contain receptors or ligands and are formed to be spaced apart from each other in a reaction solution containing a ligand or receptor labeled with a labeling substance, simultaneously inserting a plurality of electrodes into all of the plurality of absorptive regions containing the receptors or ligands and sequentially applying a positive voltage to one of the electrodes at a time while other electrodes are grounded, thereby conducting a receptor-ligand association reaction. According to the this method, it is possible to efficiently react a ligand or receptor with receptors or ligands fixed in the plurality of absorptive regions of the biochemical analysis unit and produce biochemical analysis data having an excellent quantitative characteristic with good repeatability.
A method for conducting a receptor-ligand association reaction comprising steps of dipping a biochemical analysis unit including a substrate formed with a plurality of absorptive regions which contain receptors or ligands and are formed to be spaced apart from each other in a reaction solution containing a ligand or receptor labeled with a labeling substance, inserting at least one electrode into at least one of the plurality of absorptive regions of the biochemical analysis unit and applying a positive voltage to the at least one electrode.
A reactor for conducting a receptor-ligand association reaction comprising a reaction vessel adapted for accommodating a reaction solution containing a ligand or receptor labeled with a labeling substance and provided with a holding section for holding a biochemical analysis unit including a substrate formed with a plurality of absorptive regions which contain receptors or ligands and are formed to be spaced apart from each other, an electric field generating device including a plurality of electrodes disposed at positions corresponding to those of the plurality of absorptive regions of the biochemical analysis unit held by the holding section of the reaction vessel, a positive power source, a ground terminal and a switching means for selectively connecting the plurality of electrodes to the positive power source or the ground terminal, a drive means for moving the electric field generating device between an electric field generating position where the plurality of electrodes are inserted into the corresponding absorptive regions of the biochemical analysis unit held by the holding section of the reaction vessel and a retracted position where the plurality of electrodes are retracted from the corresponding absorptive regions of the biochemical analysis unit held by the holding section of the reaction vessel, and a control means for on and off controlling the positive power source and controlling the switching means.
A reactor for conducting a receptor-ligand association reaction comprising a reaction vessel adapted for accommodating a reaction solution containing a ligand or receptor labeled with a labeling substance and provided with a holding section for holding a biochemical analysis unit including a substrate formed with a plurality of absorptive regions which contain receptors or ligands-and are formed to be spaced apart from each other, a positive power source, an electric field generating device including at least one electrode connected to the positive power source, and an electrode driving means for moving the at least one electrode between a reaction position where the at least one electrode is inserted into the corresponding absorptive region of the biochemical analysis unit held by the holding section of the reaction vessel and a retracted position where the at least one electrode is retracted from the corresponding absorptive region of the biochemical analysis unit held by the holding section of the reaction vessel, the reactor for conducting a receptor-ligand association reaction further comprising a scanning mechanism for sequentially moving the at least one electrode of the electric field generating device to positions facing the respective absorptive regions of the biochemical analysis unit held by the holding section of the reaction vessel and a control means for controlling the scanning mechanism and the electrode driving means.
Dependencies are inferred from the claim text.