US 2003/0143630 A1 · Apparatus and method for synthesizing

Abstract

An apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds such that the chemical composition of each compound is easily tracked. The library compounds are synthesized on solid-phase supports, which are spatially arranged in frames during synthesis according to a predetermined protocol, such that each solid-phase support passes through a series of unique spatial 2D or 3D addresses by which the chemical composition of each compound may be determined at any point during synthesis. Solid-phase supports include hollow tubular-shaped lanterns and gears.

Claims13

Dependent claims

A system for synthesizing a combinatorial library comprising:

a containment device with a plurality of channels, each channel fluidly connected to the outside of the containment device through an opening;
free solid supports, wherein the solid supports are sized to stack inside the plurality of channels and thereby create a columns of supports, wherein the spatial arrangement of the solid supports in channels defines a 3-D array;
and
means for removing the solid supports through said channel, retaining the spatial relationship of the supports with each other.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

10/317,178Filed 11 Dec 2002

Priority

20 May 1998

Published

31 Jul 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification50 codes

G01N 33/543
Immunoassay; Biospecific binding assay; Materials therefor: with an insoluble carrier for immobilising immunochemicals
B01J 19/0046
Chemical, physical or physico-chemical processes in general; Their relevant apparatus: sequential or parallel reactions, e.g. for the synthesis of…
B82Y 30/00
Nanotechnology for materials or surface science
B01J 2219/00286
Individual reactor vessels: reactor vessels with top and bottom openings

Family

Application09/082,038Continuation in part · filed 20 May 1998

Application09/449,222Division · filed 24 Nov 1999

Application09/449,222Continuation in part · filed 24 Nov 1999

Application10/317,178Division · filed 11 Dec 2002

US 2003/0068644 A1Published application

US 6,541,211 B1Related patent

US 6,872,535 B2Related patent

US 2003/0143630 A1This patent

From the US filing history. Foreign family members aren’t listed.

Apparatus and method for synthesizing

Life of this patent

Apparatus and method for synthesizing

Life of this patent

Abstract

Claims13