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US 2003/0143621 A1Published application
Nuclear matrix proteins
AssigneeThe Johns Hopkins University School of Medicine
InventorsDonald S. Coffey, Alan W. Partin, Robert H. Getzenberg
Life of this patent
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Abstract
Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
Claims10
A method for detecting a cell proliferative disorder in a subject comprising contacting a cellular component with a reagent which binds to PC-1 (prostate cancer-1) protein.
Dependencies are inferred from the claim text.