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US 2003/0143611 A1Published application
Polynucleotides encoding proteins mediating switch recombination
OwnerMatthias Wabl, Rolf Jessbergerinventors
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Abstract
The present invention relates to the isolation, purification and characterization of proteins mediating switch recombination. It further relates to recombinant SRTA-70 proteins, DNA sequences encoding these proteins, vectors containing these DNA sequences and hosts containing these vectors. The use of these proteins for identifying agonists or antagonists and other proteins involved in class switch recombination is also provided.
Claims21
Isolated DNA sequences encoding SRTA-70 proteins or fragments thereof.
The use of protein PARP as a regulator of the recombinative functions of B23 and SRTA-70.
The invention as hereinbefore described.
Dependencies are inferred from the claim text.