Compositions containing folic acid and reduced folate
AssigneeBASF SE
InventorsWolfgang Hahnlein, Klaus Kramer, Oliver Hasselwander, Loni Schweikert
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Abstract
Compositions are proposed which comprise folic acid in combination with 5-methyltetrahydrofolic acid, and also compositions which comprise folic acid, 5-methyltetrahydrofolic acid and/or 5-methyltetrahydrofolylpolyglutamate and also comprise a dietary component and/or a nutrient preparation, and their use is also proposed.
Claims14
A composition comprising
- (a) folic acid
- (b) 5-methyltetrahydrofolic acid and/or 5-methyltetrahydrofolylpolyglutamate
- (c) a dietary component and/or a nutrient preparation
- in which, if (c) is a dietary component, the amount of (b) in the composition (=Z) is greater than the amount of (b) in the dietary component (=N)
- (d) vitamin B6 and/or vitamin B12.
A composition comprising
- (a) folic acid
- (b) 5-methyl-(6S)-tetrahydrofolic acid and/or 5-methyl-(6S)-tetrahydrofolylpolygutamate.
A composition as claimed in at least one of the preceding claims, wherein it further comprises at least one compound which is selected from the group consisting of
- tetrahydrofolic acid;
- dihydrofolic acid;
- 5-formyltetrahydrofolic acid;
- 10-formyltetrahydrofolic acid;
- 5,10-methylenetetrahydrofolic acid;
- 5,10-methenyltetrahydrofolic acid and
- 5-formiminotetrahydrofolic acid and their polyglutamate derivatives.
A composition as claimed in at least one of the preceding claims, wherein it comprises one or more vitamins as further constituents.
A composition as claimed in at least one of the preceding claims, wherein it contains S-adenosylmethionine as further constituent.
The use of a composition comprising (a) folic acid and (b) 5-methyltetrahydrofolic acid for the prevention and/or treatment of cardiovascular disorders in patients having chronic kidney failure.
Dependencies are inferred from the claim text.