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US 2003/0143207 A1Published application
Remodeling of tissues and organ
OwnerStephen A. Livesey, David J. McQuillan +3inventors
InventorsStephen A. Livesey, David J. McQuillan, Herbert Daniel Beniker, Lawrence E. Boerboom, Warren O. Haggard
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Abstract
The invention provides methods of repairing damage to, or defects in, mammalian tissues or organs. In these methods, a particulate or non-particulate acellular matrix made from a tissue or organ other than the tissue or organ being repaired is placed in or on the organ or tissue that is being repaired.
Claims30
A method of treatment, comprising
- (a) identifying a mammalian subject as having a recipient organ, or tissue, in need of repair or amelioration;
- and
- (b) placing a composition comprising a non-particulate acellular matrix made from a donor collagen-based tissue in or on the recipient organ or tissue;
- wherein the recipient organ or tissue is selected from the group consisting of skin, bone, cartilage, meniscus, dermis, myocardium, periosteum, artery, vein, stomach, small intestine, large intestine, diaphragm, tendon, ligament, neural tissue, striated muscle, smooth muscle, bladder, ureter, urethra, and abdominal wall fascia, and
- wherein the recipient organ or tissue is different from the donor collagen-based organ or tissue.
2 more elements
A method of treatment, comprising
- (a) identifying a mammalian subject as having a recipient organ, or tissue, in need of repair or amelioration;
- and
- (b) placing a composition comprising a particulate acellular matrix made from a donor collagen-based organ or tissue in or on the recipient organ or tissue;
- wherein the recipient organ or tissue is selected from the group consisting of skin, bone, cartilage, meniscus, dermis, myocardium, stomach, small intestine, large intestine, diaphragm, tendon, ligament, neural tissue, striated muscle, smooth muscle, bladder, and gingiva, and
- wherein the recipient organ or tissue is different from the donor collagen-based organ or tissue.
2 more elements
Dependencies are inferred from the claim text.