Method of treatment of anorectal disorders
OwnerDenis Kinginventor
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Abstract
A method of treatment of an anal disease, said method including the step of increasing the level of at least one isoform of the enzyme nitric oxide synthase in the cells of the ano-rectal region of a subject in need of such treatment.
Claims22
A method of treatment of an anal disease, said method including the step of increasing the level of at least one isoform of the enzyme nitric oxide synthase in the cells of the ano-rectal region of a subject in need of such treatment.
The method of any one of the preceding claims wherein the at least one isoform of NOS is an inducible isoform of NOS.
The method of any one of the preceding claims wherein the level of the at least one isoform of NOS is increased by topically applying a formulation including the nucleotide sequence encoding the at least one isoform of nitric oxide synthase and a pharmaceutically acceptable carrier to the skin of the perianal region or the lining of the anal canal.
An isolated nucleotide sequence encoding at least one isoform of nitric oxide synthase (NOS) for use in the manufacture of a medicament for the treatment of an anal disease.
Dependencies are inferred from the claim text.