Back to results
US 2003/0143132 A1Published application
Reduced length kaleidoscopic light homogenizer
AssigneeNimblegen Systems Inc.
InventorsFrancesco Cerrina, Wei Huang
Life of this patent
Estimating the term…
Abstract
The present invention provides an apparatus for constructing arrays of DNA sequences using the image of a micromirror array projected on a reaction site using a highly uniform beam of light produced by a homogenizer formed of a prismatic refractive element followed by a kaleidoscopic element.
Claims10
An apparatus for constructing DNA probes comprising:
- (a) a reactor providing a reaction site at which nucleotide addition reactions may be conducted;
- (b) a light source providing a light capable of promoting nucleotide addition reactions;
- (c) a set of electronically addressable micromirrors positioned along an optical path between the light source and the reactor to receive and reflect the light;
- and
- (d) a prismatic/kaleidoscopic light homogenizer positioned on the optical path between the light source and the electronically addressable micromirrors, the prismatic/kaleidoscopic light homogenizer having a light transmitting refractive prism followed by an internally reflecting kaleidoscope element, the latter positioned to received light refracted by the refractive prism.
2 more elements
An apparatus for catalyzing a reaction on a substrate comprising:
- a light source;
- a micromirror positioned to redirect light from said light source toward said substrate;
- a prismatic/kaleidoscopic homogenizer positioned between said light source and said micromirror and having a light transmitting refractive prism followed by an internally reflecting kaleidoscope element positioned to received light refracted by the refractive prism;
- a computer connected to, and controlling, said micromirror, and a reaction chamber is placed in the path of light redirected by said micromirror, wherein light that is redirected by said micromirror catalyzes a chemical reaction proximate said substrate in said reaction chamber.
1 more element
Dependencies are inferred from the claim text.