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AssigneeBristol-Myers Squibb Company
InventorsWaldemar Ruediger, A. Erik Rubin, Alexander Bertok, Victor W. Rosso, Joseph Nolfo, Harold N. Weller
Estimating the term…
The base of the modular reactor includes a frame which defines an opening into which one of a plurality of interchangeable reaction vessel carrying inserts can be removeably received. Each insert has an array of recesses adapted to receive a different number of reaction vessels of different sizes. The recesses are positioned such that all arrays are suitable for use with a standard automated liquid handier. The frame has fluid flow channels for regulating the temperature of the lower portions of the vessels. A temperature control module can be received over the base to regulate the temperature of the upper portions of the vessels for reflux reactions. The corner radii of the insert and frame opening cooperate to permit the insert to be received in the frame in only one orientation. The walls of the insert are inclined to facilitate removal by a friction fit tool. Each vessel receiving recess has a self-centering conical or semi-circular shaped bottom to maximize heat transfer and distribute the load uniformly. The vessels seat as close to the bottom surface of the base as possible to facilitate use with an air driven magnetic stirrer. A thin, electrically heated plate may be received between the base and the stirrer.
Apparatus for performing process chemistry reactions in a plurality of reaction vessels comprising:
Apparatus for performing process chemistry reactions in a plurality of reaction vessels comprising:
A reaction vessel carrying insert adapted for use in apparatus for performing parallel chemistry reactions, the apparatus having a base comprising a frame with a wall defining an insert receiving opening, said insert being adapted to be removably received within said insert receiving opening in only a single orientation and comprising an array of reaction vessel receiving recesses.
Magnetic stirrer means for use in combination with a parallel chemistry reactor, said stirrer means comprising a body with an opening, an impeller freely rotatably received within said opening, magnetic means associated with said impeller and means for rotating said impeller.
An extraction tool for use with a vessel receiving insert adapted to be removably received within an opening in the frame of modular apparatus for performing parallel chemistry reactions, said insert comprising a recess, said tool comprising an expandable protrusion and means for causing said protrusion to change between an expanded state, wherein said protrusion engages said recess, and a non-expanded state, wherein said recess is released.
Dependencies are inferred from the claim text.