Polynucleotide vaccine formula against canine pathologies, in particular respiratory and digestive pathologies
AssigneeMerial Limited
InventorsJean-Christophe Audonnet, Annabelle Bouchardon, Michel Riviere
Life of this patent
Estimating the term…
Abstract
Disclosed is an immunological or vaccine composition that includes at least one plasmid that contains and expresses in vivo in host canine cells a nucleic acid molecule that encodes an antigen of a canine pathogen, such as rabies G. The plasmid can include more that one nucleic acid molecule such that the plasmid can express more than one antigen. Also disclosed are methods for using and kits employing such compositions.
Claims28
A Canidae vaccine comprising an effective amount of a plasmid that contains and expresses in a Canidae host cell a nucleic acid molecule having a nucleic acid sequence encoding rabies G, and a pharmaceutically acceptable carrier, wherein the vaccine provides protection of at least one year against rabies G.
An immunogenic composition for inducing in a canine host an immunological response against a canine pathogen comprising a plasmid that contains and expresses in vivo in a canine host cell a nucleic acid molecule having a sequence encoding an antigen of a canine pathogen, wherein the composition is in a needleless injection.
A method for inducing an immunological response in a canine against a canine pathogen comprising administering to the canine an immunogenic composition that comprises a plasmid that contains and expresses in vivo in a canine host cell a nucleic acid molecule having a sequence encoding an antigen of the canine pathogen by a needleless injection.
23 A needlelesss injection apparatus that administers a composition:
- without a needle, wherein the apparatus includes an immunogenic composition for inducing in a canine host an immunological response against a canine pathogen comprising a plasmid that contains and expresses in vivo in a canine host cell a nucleic acid molecule having a sequence encoding an antigen of a canine pathogen.
Dependencies are inferred from the claim text.