Diester compounds of maleic acid (or fumaric acid)
AssigneeSenju Pharmaceutical Co., Ltd.
InventorsKazumi Ogata, Noriko Saito, Shinya Ogino
Life of this patent
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Abstract
According to the present invention, there are provided diester compounds of maleic acid (or fumaric acid) or their pharmacologically acceptable salts represented by the formula: 1 (wherein each of R1 and R2 each is the same as, or different from, the other, and designates a hydrogen atom or methyl group), which are useful as a cosmetic constituent, antioxidant, radical scavenger or anti-inflammatory agent.
Claims29
A diester compound of maleic acid (or fumaric acid) illustrated by the following formula or its pharmacologically acceptable salt:
- 3
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A method for absorbing ultraviolet radiation or suppressing deposition of melanin pigment which comprises applying to the skin in need thereof a diester compound of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 4
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A method for suppressing oxidation or scavenging radicals which comprises administering to a subject in need thereof an effective amount of a diester compounds of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 5
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A method for preventing or treating inflammations which comprises administering to a subject in need thereof an effective amount of a diester compound of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 6
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A use in the manufacture of cosmetics of a diester compound of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 7
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A use in the manufacture of antioxidants or radical scavengers of a diester compound of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 8
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A use in the manufacture of pharmaceuticals of a diester compound of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 9
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
A use in the manufacture of anti-inflammatory agents of a diester compound of maleic acid (or fumaric acid) or its pharmacologically acceptable salt illustrated by the following formula:
- 10
- (wherein each of R1 and R2 each is the same as, or different from, the other and designates a hydrogen atom or methyl group).
Dependencies are inferred from the claim text.