Back to results
US 2003/0125571 A1Published application
Optically active chroman and thiochroman derivatives
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsSungDae Park, HeeAn Kwon, HongKi Kim, PilSu Ho, Kazumi Morikawa, Yoshitake Kanbe, Masahiro Nishimoto, MyungHwa Kim
Life of this patent
Estimating the term…
Abstract
The present invention includes a compound having the following general formula (1): 1 in which X represents an oxygen atom or a sulfur atom, m represents an integer of 2 to 14, and n represents an integer of 2 to 7, or hydrates or pharmaceutically acceptable salts thereof. The compound of general formula (1) is advantageous in pharmaceutical use because of its far superior anti-estrogenic activity over the corresponding racemic mixture.
Claims13
A compound having the following general formula (1):
- 41
- in which
- X represents an oxygen atom or a sulfur atom,
- m represents an integer of 2 to 14, and
- n represents an integer of 2 to 7,
- or the following general formula (2):
- 42
- in which
- X represents an oxygen atom or a sulfur atom,
- m represents an integer of 2 to 14, and
- n represents an integer of 2 to 7,
- or the following general formula (3):
- 43
- in which
- X represents an oxygen atom or a sulfur atom,
- m represents an integer of 2 to 14, and
- n represents an integer of 2 to 7,
- or the following general formula (4):
- 44
- in which
- X represents an oxygen atom or a sulfur atom,
- m represents an integer of 2 to 14, and
- n represents an integer of 2 to 7,
- or a hydrate thereof.
21 more elements
Dependencies are inferred from the claim text.