Back to results
US 2003/0125562 A1Published application
Methods of producing 4-amino-3-mercapto-triazoles
OwnerNed H. Heindel, Jeffrey D. Laskin +3inventors
InventorsNed H. Heindel, Jeffrey D. Laskin, Diane E. Heck, Christophe Guillon, Robert D. Rapp
Life of this patent
Estimating the term…
Abstract
This invention claims the process for producing two structural variants of functionalized 4-amino-3-mercapto-1,2,4-triazoles as inhibitors of nitric oxide synthase (NOS) and as inhibitors of malignant cell growth. This fundamental molecular construct operates as a heterocyclic mimic of the open-chain N-aminoarginines (or N-aminoguanidines) previously established as NOS inhibitors.
Claims11
Compounds as described below and in each class, R and R′ may constitute alkyl, aryl, hydrogen, halogen, fluoroalkyl, or heterocyclic.
- 4
Dependencies are inferred from the claim text.