Photodynamic therapy for the treatment of epilepsy
OwnerEdie Zusmaninventor
Life of this patent
Estimating the term…
Abstract
The present invention is based on the discovery that cells associated with seizure have selective intake of photoactive compounds. The present invention provides methods of triggering cell death in cells associated with seizure conditions by exposing such cells to photoactive compounds and irradiating the photoactive compounds contained within the cells. The present invention also provides methods of labeling cells associated with seizure conditions by exposing such cells with photoactive compounds. In addition, the present invention provides model systems useful for studying seizure conditions.
Claims52
A method of triggering a cell death process in a cell associated with a seizure condition comprising exposing the cell to a photoactive compound and irradiating the cell with an energy source comprising at least one wavelength capable of being absorbed by the photoactive compound, whereby triggering a cell death process in the cell.
A method of treating a seizure condition comprising administering to a subject in need of such treatment an effective amount of a photoactive compound and irradiating cells associated with the seizure condition with an energy source comprising at least one wavelength capable of being absorbed by the photoactive compound.
A method of labeling a cell associated with a seizure condition comprising exposing a population of cells to a photoactive compound, whereby a cell associated with a seizure condition is labeled by up-taking the photoactive compound.
A kit comprising a photoactive compound and an instruction for using the photoactive compound to trigger a cell death process in cells associated with a seizure condition.
A kit comprising a photoactive compound and an instruction for labeling cells associated with a seizure condition.
A neural model system useful for studying a seizure condition wherein cells associated with the seizure condition are selectively reduced by being exposed to a photoactive compound and irradiated by an energy source comprising at least one wavelength capable of being absorbed by the photoactive compound.
Dependencies are inferred from the claim text.