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US 2003/0125281 A1Published application
Compositions and processes using siRNA, amphipathic compounds and polycations
AssigneeMirus Bio Corporation
InventorsDavid Lewis, James E. Hagstrom, Hans Herweijer, Aaron G. Loomis, Sean D. Monahan, Jon A. Wolff
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Abstract
Described is a deliverable composition with low toxicity comprising an amphipathic compound, a polycation, and a siRNA. The composition may be used in the process of delivering a siRNA to an animal cell or more particularly, a mammal cell.
Claims17
A deliverable composition comprising:
- an amphipathic compound, a polycation, and a siRNA.
A process of delivering a siRNA to an animal cell comprising:
- associating the cell with a composition comprising an amphipathic compound, an effective amount of a polycation, and a siRNA in solution.
Dependencies are inferred from the claim text.