Antisense modulation of human collapsin response mediator protein 2 expression
AssigneeIsis Pharmaceuticals, Inc.
InventorsWilliam Gaarde, Andrew T. Watt
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of human collapsin response mediator protein 2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding human collapsin response mediator protein 2. Methods of using these compounds for modulation of human collapsin response mediator protein 2 expression and for treatment of diseases associated with expression of human collapsin response mediator protein 2 are provided.
Claims20
A compound 8 to 50 nucleobases in length targeted to a nucleic acid molecule encoding human collapsin response mediator protein 2, wherein said compound specifically hybridizes with said nucleic acid molecule encoding human collapsin response mediator protein 2 and inhibits the expression of human collapsin response mediator protein 2.
A compound 8 to 50 nucleobases in length which specifically hybridizes with at least an 8-nucleobase portion of an active site on a nucleic acid molecule encoding human collapsin response mediator protein 2.
Dependencies are inferred from the claim text.