Enzymatic nucleic acid treatment of diseases or conditions related to hepatitis C virus infection
OwnerLawrence Blatt, James McSwiggen +3inventors
InventorsLawrence Blatt, James McSwiggen, Elisabeth Roberts, Pamela A. Pavco, Dennis Macejack
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Abstract
Enzymatic nucleic acid molecules (e.g., ribozymes and DNAzymes) that modulate the expression and/or replication of hepatitis C virus (HCV).
Claims38
An enzymatic nucleic acid molecule which specifically cleaves RNA derived from hepatitis C virus (HCV), wherein the binding arms of said enzymatic nucleic acid molecule comprises sequences complementary to any of substrate sequences defined as Seq. ID Nos. 1-4554, 4556-4640, and 4683-4797.
An enzymatic nucleic acid molecule which specifically cleaves RNA derived from hepatitis C virus (HCV), wherein said enzymatic nucleic acid molecule comprises sequences defined as Seq. ID Nos. 4798-9352, 9354-9442, and 9485-9636.
Dependencies are inferred from the claim text.