Stabilized medicament containing cysteinyl derivatives
OwnerFritz Stanislausinventor
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Abstract
The invention relates to a stabilized medicament with an amount of active ingredients containing cysteine groups and NSAID compounds, wherein a stabilization of the combination, especially the active ingredients containing the cysteine group, can be conducted with a mixture of at least three anti-oxidative components. The therapeutic and prophylactic use of this medicament stabilized in this manner lies in the field of the prevention and therapy of inflammatory diseases among the fields of medical indications.
Claims16
Stabilized medicament with an amount of cysteinyl or dicysteinyl compounds, particularly N-acetylcysteine, against broncial and pulmonary diseases, and/or glutathione, optionally in combination with a non-steroid antiphlogistic agent/analgesic agent (NSAID), especially Diclofenac, for suppressing organ, especially liver, damage and inflammation damage as sole active ingredient(s), containing a stabilizer mixture comprising at least 3 components from the series
- a) ascorbic acid (vitamin C) or salts or esters thereof,
- b) one or more tocopherols (vitamin E),
- c) one or more carotinoids and/or vitamin A,
- d) one or more natural or synthetic flavonoids, bioflavonoids, flavanols or catechins including anthocyanenes and glycosides thereof
- as well as pharmaceutically acceptable additives and/or carrier agents for per oral, topical, parenteral or rectal administration forms if required.
Use of cysteinyl or dicysteinyl compounds, particularly N-acetylcysteine and/or glutathione together with a stabilizer mixture comprising at least 3 components from the series
- a) ascorbic acid (vitamin C) or salts or esters thereof,
- b) one or more tocopherols (vitamin E),
- c) one or more carotinoids and/or vitamin A,
- d) one or more natural or synthetic flavonoids, bioflavonoids, flavanols or catechins including anthocyanenes and glycosides thereof
- as well as pharmaceutically acceptable additives and/or carrier agents for per oral, topical, parenteral or rectal administration forms if required, optionally in combination with a non-steroid antiphlogistic agent/analgesic agent (NSAID), especially Diclofenac, as sole active ingredient(s) for the production of medicaments for the therapeutic or prophylactic treatment of inflammatory diseases of the respiratory tract and for suppression of organ and inflammation damage, particularly of the liver.
Use of a mixture, comprising at least 3 components of the series
- a) ascorbic acid (vitamin C) or salts or esters thereof,
- b) one or more tocopherols (vitamin E),
- c) one or more carotinoids and/or vitamin A,
- d) one or more natural or synthetic flavonoids, bioflavonoids, flavanols or catechins including anthocyanenes and glycosides thereof
- for the stabilization of medicines with an amount of one or more cysteinyl compounds, particularly N-acetylcysteine, as well as pharmaceutically acceptable additives and/or carrier agents for per oral, topical, parenteral or rectal administration forms if required, optionally in combination with one or more NSAID compounds, especially Diclofenac.
Dependencies are inferred from the claim text.