Flavone derivatives, preparation method and use as medicines

1) Products of formula (I):

• 8
• in which:
• R1 represents a carbocyclic or heterocyclic monocyclic or bicyclic radical containing at most 12 members, saturated or unsaturated, containing one or more identical or different heteroatoms chosen from O, N, NH or S and can contain a —C(O) member,
• the carbocyclic and heterocyclic radicals as defined above for R1, being optionally substituted by one or more radicals chosen from halogen atoms;
• the hydroxyl;
• cycloalkyl containing at most 6 members;
• acyl containing at most 7 carbon atoms;
• cyano;
• nitro;
• free, salified or esterified carboxy;
• tetrazolyl;
• —NH2, —NH(alk), —N(alk)(alk);
• SO2—NH—CO—NHR5 in which R5 represents an alkyl or phenyl radical;
• —C(O)—NH2, —C(O)—NH(alk), —C(O)—N(alk)(alk), —NH—C(O)—(alk), —N(alk)—C(O)—(alk);
• thienyl;
• phenyl;
• alkylphenyl;
• alkyl, alkenyl, alkylthio, alkoxy or phenoxy radicals themselves optionally substituted by one or more radicals chosen from halogen atoms, the —NH2, —NH(alk), —N(alk)(alk) radicals and the heterocyclic monocyclic or bicyclic radicals themselves optionally substituted by one or more radicals chosen from alkyl radicals and halogen atoms,
• R2 and R3 are such that one represents a hydrogen atom and the other represents a piperidinyl radical optionally substituted by one or more hydroxyl and alkyl radicals,
• R2 and R3 being alternatively able to take the same values in order to produce the corresponding isomers,
• R4 represents a hydrogen atom, an alkyl or phenyl radical optionally substituted by one or more halogen atoms it being understood that in the above radicals, the alkyl and alkoxy radicals are linear or branched and contain at most 6 carbon atoms,
• said products of formula (I) being in all possible racemic, enantiomeric and diastereoisomeric isomer forms, as well as the addition salts with mineral and organic acids or with mineral and organic bases of said products of formula (I).