Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
AssigneeSchering Corporation
InventorHarry R. Davis
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Abstract
The present invention provides therapeutic combinations and methods including at least one sterol or 5α-stanol absorption inhibitor that can be useful for treating xanthomas.
Claims23
A method of preventing or decreasing the incidence of xanthomas in a subject comprising the step of administering to a subject in need of such treatment an effective amount of at least one sterol absorption inhibitor, at least one 5α-stanol absorption inhibitor, or a pharmaceutically acceptable salt or solvate thereof to prevent or decrease the incidence of xanthomas in the subject.
A therapeutic combination comprising (a) a first amount of at least one sterol absorption inhibitor, at least one 5α-stanol absorption inhibitor, or a pharmaceutically acceptable salt or solvate thereof and (b) a second amount of at least one cholesterol biosynthesis inhibitor, wherein the first amount and the second amount together comprise a therapeutically effective amount for the treatment or prevention of xanthomas in a subject.
Dependencies are inferred from the claim text.