Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
AssigneeSchering Corporation
InventorJohn T. Strony
Life of this patent
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Abstract
The present invention provides compositions, therapeutic combinations and methods including: (a) at least one hormone replacement therapy composition; and (b) at least one sterol absorption inhibitor which can be useful for treating vascular conditions in post-menopausal women and lowering plasma levels of sterols or 5α-stanols.
Claims44
A composition comprising:
- (a) at least one hormone replacement therapy composition;
- and
- (b) at least one sterol or 5α-stanol absorption inhibitor or a pharmaceutically acceptable salt thereof or a solvate thereof.
A therapeutic combination comprising:
- (a) a first amount of at least one hormone replacement therapy composition;
- and
- (b) a second amount of at least one sterol or 5α-stanol absorption inhibitor or a pharmaceutically acceptable salt thereof or a solvate thereof, wherein the first amount and the second amount together comprise a therapeutically effective amount for the treatment or prevention of a vascular condition, hypertension, diabetes, obesity, lowering a concentration of a sterol or 5α-stanol in plasma of a subject or as a hormone replacement therapy/vascular condition treatment for a subject.
A hormone replacement therapy/vascular condition treatment composition comprising:
- (a) at least one hormone replacement therapy composition;
- and (b) at least one sterol or 5α-stanol absorption inhibitor or a pharmaceutically acceptable salt thereof or a solvate thereof.
A method of treating a vascular condition, hypertension, obesity, or lowering a concentration of a sterol or 5α-stanol in plasma of a post menopausal woman, comprising administering to a post menopausal woman at least one sterol or 5α-stanol absorption inhibitor or a pharmaceutically acceptable salt thereof or a solvate thereof.
Dependencies are inferred from the claim text.