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US 2003/0119730 A1Published application
Human phospholipid binding proteins
AssigneeIncyte Pharmaceuticals, Inc.
InventorsPreeti Lal, Jennifer L. Hillman, Neil C. Corley, Purvi Shah
Life of this patent
Estimating the term…
Abstract
The invention provides two human phospholipid binding proteins (PLBP) and polynucleotides which identify and encode PLBP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of PLBP.
Claims48
An isolated polypeptide selected from the group consisting of:
- a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:3,
- b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:3,
- c) a polypeptide comprising a biologically active fragment of an amino acid sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:3, and
- d) a polypeptide comprising an immunogenic fragment of an amino acid sequence selected from the group consisting of SEQ ID NO:1 and SEQ ID NO:3.
1 more element
An isolated polynucleotide selected from the group consisting of:
- a) a polynucleotide comprising a polynucleotide sequence selected from the group consisting of SEQ ID NO:2 and SEQ ID NO:4,
- b) a polynucleotide comprising a naturally occurring polynucleotide sequence at least 90% identical to a polynucleotide sequence selected from the group consisting of SEQ ID NO:2 and SEQ ID NO:4,
- c) a polynucleotide complementary to a polynucleotide of a),
- d) a polynucleotide complementary to a polynucleotide of b), and
- e) an RNA equivalent of a)-d).
2 more elements
Dependencies are inferred from the claim text.