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AssigneeBoard of Regents
InventorsPeter R.C. Gascoyne, Jody Vykoukal, Daynene Vykoukal, Susan Sharma, Frederick F. Becker
Estimating the term…
Engineered microparticles, libraries of microparticles, and methods relating thereto. The microparticles are distinguishable based on differences in dielectric response to an applied electric field. In different embodiments, the dielectric differences may be engineered through, but not limited to, dielectrically dispersive materials, surface charge, and/or fluorescence. Gangliosides may be incorporated with the microparticles to control aggregation. Vesicles including erythrocyte ghosts may be used as a basis for microparticles. The microparticles may utilize a biotin streptavidin system for surface functionalization.
An engineered microparticle fabricated to be dielectrically-dispersive and adapted to produce a dielectric response to an applied electric field such that the microparticle is maneuverable by dielectrophoresis.
A library of two or more engineered microparticles, each microparticle comprising a dielectrically-dispersive material differing to an extent sufficient to cause a discernible difference in a dielectric response of each microparticle to an applied electric field.
A method for forming a library of two or more engineered microparticles, comprising:
An engineered microparticle comprising one or more gangliosides to affect microparticle aggregation.
A method for controlling the aggregation of microparticles, comprising modulating the surface charge of one or more of the microparticles.
A method for identifying one or more complexes within a sample, the method comprising:
Dependencies are inferred from the claim text.