Universal collection medium
AssigneeDigene Corporation
InventorsAttila T. Lorincz, Yanlin Tang
Life of this patent
Estimating the term…
Abstract
This invention provides a novel universal collection medium for cell collection. The medium allows for the first time.the ability to perform cytology and direct molecular analysis on cells preserved in a single sample. This invention also provides novel methods for analyzing cells to assess human conditions.
Claims28
A cell or tissue collection medium or a universal collection medium, wherein the cells or tissue contained in the medium can be analyzed directly by both cytological and molecular methods, wherein the molecular method of analysis comprises either RNA or DNA or protein analysis or the analysis of both RNA and DNA, and wherein the medium is water based and comprises a preservative, a fixative and an anti-degradation agent.
A method of performing morphological and biochemical analysis on a cell or tissue, wherein the method comprises:
- obtaining cells or tissues from a patient;
- preserving the cells or tissue in a water-based medium comprising a preservative, a fixative and an anti-degradation agent;
- directly analyzing the morphology of the cells or tissue preserved in the medium;
- and
- directly analyzing either RNA or DNA or protein contained in the cells or tissue preserved in the medium.
A universal collection medium comprising water, a preserving agent, a buffer, a fixative and an agent capable of inhibiting the degradation of at least one of the group consisting of RNA, DNA and protein.
Dependencies are inferred from the claim text.